Sinagapore Airlines independently operated daily B747-400 service from San Francisco (KSFO) to Singapore (WSSS) with continuing service to Hong Kong Kai Tak (VHHX). This flight had connections from TWA service to/from San Francisco.

Singapore Airlines also operated daily B747-400 service from Amsterdam (EHAM) via Bombay (VABB) to Singapore (WSSS). TWA had connecting service at Amsterdam to/from Singapore Airlines.